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產(chǎn)品名稱: Recombinant Human IL-4
產(chǎn)品型號: 200-04-10
產(chǎn)品展商: Peprotech
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
Recombinant Human IL-4,中文名稱：重組人白介素-4，規(guī)格：10ug，貨號：200-04
Recombinant Human IL-4
的詳細介紹
Recombinant Human IL-4：
Synonyms : BCGF, BCDF, B cell stimulating factor (BSF-1) Description : IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues.
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